Explore our elite selection of scientifically standardized natural ingredients, refined to perfection under GMP and ISO certifications.
Established in 2012, Chengdu Chenlv Herb Co., Ltd. (hereinafter referred to as "Chenlv Herb") is a high-tech pioneer specialized in the research, development, industrial-scale extraction, and distribution of premium botanical extracts and natural active pharmaceutical ingredients (APIs).
With a focus on isolating and purifying natural compounds such as Frangula Emodin, we serve an elite international client portfolio across the pharmaceutical, nutraceutical, cosmeceutical, and functional animal nutrition sectors. Our core mission is defined by providing high-purity, standardized botanical derivatives that meet the rigorous scientific requirements of contemporary global supply chains.
Our modernized production infrastructure is calibrated to bridge laboratory precision with massive agricultural raw material handling capacity.
Unlocking the cellular potency of 1,3,8-trihydroxy-6-methylanthraquinone for advanced applications.
Traditional extraction often suffers from low yields and the co-extraction of undesirable anthraquinones like physcion and chrysophanol. Chenlv Herb utilizes a modified hydro-alcoholic maceration coupled with counter-current liquid-liquid extraction. The crude extract undergoes acid hydrolysis to convert emodin glycosides into their free aglycone form, followed by precise recrystallization using food-grade organic solvents. This process yields Frangula Emodin at assays up to 98% by HPLC, maintaining solvent residues far below EP and USP guidelines.
A primary challenge of Emodin is its low aqueous solubility and rapid first-pass metabolism, which limits its in vivo therapeutic efficacy. Our R&D team is actively commercializing formulation solutions such as microfluidic-assisted nano-emulsions, solid dispersions utilizing PVP/PEG matrices, and beta-cyclodextrin inclusion complexes. These advanced delivery systems enhance the dissolution rate and biological availability of Emodin, paving the way for low-dose, high-efficacy health supplements.
Looking to the next decade, Chenlv Herb is exploring biosynthetic pathways. By mapping the polyketide synthase (PKS) enzymes responsible for anthraquinone generation in *Rhamnus frangula*, we are laying the groundwork for yeast-based fermentation technologies. This sustainable, plant-free production route aims to secure a climate-resilient, consistent supply of bio-identical Emodin, bypassing the ecological pressures of wild harvesting.
Rigorous quality control and analytical validation to meet global regulatory and industrial standards.
| Specification Parameter | Standard Value / Limit | Analytical Methodology | Regulatory Compliance Status |
|---|---|---|---|
| Assay (Emodin Aglycone) | ≥ 98.0% (on dry basis) | HPLC-UV (Standard External Method) | USP / EP Grade Compliant |
| Physical Appearance | Fine, orange-yellow crystalline powder | Visual & Organoleptic Assessment | Standardized Organoleptic Spec |
| Heavy Metals (Pb, As, Cd, Hg) | Pb < 3.0 ppm, As < 1.0 ppm, Cd < 0.5 ppm, Hg < 0.1 ppm | ICP-MS (Inductively Coupled Plasma) | Prop 65 & EU Directive compliant |
| Pesticide Residues | Non-detectable / meets EC 396/2005 limits | GC-MS-MS / LC-MS-MS Screen | EU/FDA Food Grade Compliant |
| Total Aerobic Microbial Count | ≤ 1,000 CFU/g | USP <61> Microbiological examination | Pharmacopeia Standard |
| Solvent Residues | Ethanol < 5000 ppm (typically < 100 ppm) | HS-GC-MS (Headspace GC-MS) | ICH Q3C Class 3 Compliant |
Scaling production using data-driven automation, sustainable raw material integration, and risk-managed logistics.
Our facility incorporates PLC-controlled closed-loop extractors, automated film evaporators, and spray drying systems. Digitized control loops eliminate manual variance, tracking pressure, temperature, and solvent-to-material ratios in real time. This ensures consistent purity batch after batch, keeping production efficient and scalable.
We mitigate the volatility of agricultural sourcing through a diversified network of certified growers. Our raw materials are harvested according to Good Agricultural and Collection Practices (GACP). Every batch of *Rhamnus frangula* bark is certified for identity and purity before processing, protecting the surrounding ecosystems.
Global logistics demand robust supply chain risk mitigation. Through established contracts with top freight carriers and custom brokers, we offer continuous shipment tracking, proactive custom clearance documentation, and dynamic inventory warehousing. This ensures prompt deliveries to key distribution hubs in North America, Europe, and Asia.
Bridging basic botany with diverse commercial applications through high-performance natural active ingredients.
Emodin functions as an active anthraquinone laxative that increases mucosal secretion and stimulates peristalsis in the colon. In oncology, it is widely researched for its role in inducing apoptosis in cancer cells, inhibiting angiogenesis, and sensitizing tumors to conventional chemotherapeutics.
Its natural yellow tint is accompanied by potent tyrosinase-inhibiting properties. Emodin acts as an antioxidant and anti-inflammatory agent, protecting dermal structures from UV-induced degradation and reducing dark spots, making it a valuable addition to functional skincare.
As agricultural operations phase out antibiotic growth promoters (AGPs), Emodin offers a bio-active alternative. Its anti-microbial properties combat pathogens like *Salmonella* and *Clostridium perfringens* in the gut, improving feed conversion ratios and overall livestock health.
Clinical studies suggest Emodin helps regulate glucose homeostasis and lipid metabolism by activating AMPK pathways. We supply Emodin in bulk powders and ready-to-fill granulations for weight loss formulations and blood sugar support supplements.
Why global brands rely on Chenlv Herb as their primary supplier and manufacturing partner.
Custom extraction technologies that optimize active ingredient concentration and improve product purity.
Streamlined manufacturing workflows and eco-friendly packaging designed to reduce delivery lead times.
Responsibly harvested raw materials and green extraction processes designed to minimize environmental impact.
Professional technical support team offering fast turnaround times, document compilation, and regulatory guidance.
In-house testing laboratories equipped with advanced analytical instrumentation (HPLC, GC, ICP-MS) for batch verification.
Over a decade of industry expertise in plant extraction, custom formulation, and regulatory compliance.
From formulation design to large-scale production, we offer reliable contract manufacturing services.
We work closely with your technical teams to understand the required active ingredient specifications and intended applications.
We provide a comprehensive proposal and competitive commercial quotation based on raw material costs and batch sizes.
We establish formal contracts outlining quality specifications, intellectual property protection, and shipment schedules.
Our lab prepares prototype samples according to your target specifications and provides pilot-scale trial reports.
Upon sample approval, we schedule commercial production in our GMP facility, monitoring quality at every stage.
Every production batch undergoes strict quality control. We issue a comprehensive Certificate of Analysis (COA) for approval before shipping.
We package products in high-density polyethylene drums and ship them worldwide via temperature-controlled transport channels.
Verified regulatory compliance ensuring smooth customs clearance and product safety.
Our manufacturing processes comply with strict global safety standards. Chenlv Herb holds key international certifications, including ISO9001, ISO22000, HALAL, KOSHER, and FDA registration.
Stay updated with the latest plant extract market dynamics, scientific research, and trade show schedules.
With the harvest season concluding, market prices for Citrus Aurantium raw materials have risen. We analyze the balance between supply, demand, and production costs to help buyers budget effectively.
We invite pharmaceutical buyers and research partners to join us at CPHI China 2025 to discuss customization capabilities and the latest active ingredient developments.
Discover our latest research on plant-derived APIs at API China. Meet our engineering and technical teams to explore high-purity natural compound customization.
Technical and logistics questions answered by our application specialists.
Get in touch with our sales and technical support teams. We will provide pricing, product specifications, and documentation support within 24 hours.
SEND AN INQUIRY NOWExplore our full line of botanical extracts, manufactured under GMP standards to support diverse health applications.
