Premium, high-activity bile acid derivatives and key compounds processed under strict quality control guidelines.
Chengdu Chenlv Herb Co., Ltd.
Chengdu ChenLv Herb Co.,Ltd. (referred to as "Chenlv Herb") was established in 2012 as a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts and natural pharmaceutical ingredients. Committed to providing high-purity, highly active, and premium-quality natural raw materials, the company serves diverse industries, including pharmaceuticals, health supplements, food, and cosmetics.
Our commitment is built on rigorous scientific principles, state-of-the-art laboratory infrastructure, and comprehensive analytics. Over the decade, we have established robust purification pathways to derive high-purity bile acids and plant-based chemical assets, enabling developers worldwide to secure reliable supply chains for critical therapeutic research and bulk manufacturing needs.
Established In 2012 — Built upon a decade of quality-certified biomanufacturing.
Bile acids, primarily synthesized in the liver from cholesterol, have evolved from basic physiological surfactants into high-value active pharmaceutical ingredients (APIs), diagnostic reagents, and highly functional nutritional feed additives. The Cholic Acid series—which encompasses raw Cholic Acid (CA), Chenodeoxycholic Acid (CDCA), Ursodeoxycholic Acid (UDCA), Deoxycholic Acid (DCA), Tauroursodeoxycholic Acid (TUDCA), and their corresponding sodium salts—occupies a central position in modern pharmaceutical research.
Globally, the commercial importance of these compounds is driven by the growing incidence of hepatobiliary diseases, lipid metabolic disorders, and neurodegenerative illnesses. For instance, UDCA remains the first-line treatment for Primary Biliary Cholangitis (PBC) and a critical agent for gallstone dissolution. Concurrently, the synthesis of Obeticholic Acid (OCA), a potent Farnesoid X Receptor (FXR) agonist used for advanced liver pathology, relies heavily on high-purity CDCA as a starting template. In the veterinary sector, bile acid mixtures are utilized to optimize energy utilization and prevent hepatotoxicity in intensive aquaculture and poultry farming.
As strict environmental mandates and raw animal-source traceability regulations (such as BSE/TSE-free certificates) become the global standard, the supply chain for bile acids has experienced structural consolidation. B2B buyers now prioritize manufacturers capable of providing robust analytical validation, reliable regulatory dossiers (DMF, CEP), and sustainable sourcing models.
Why international pharmaceutical companies and industrial buyers choose Chenlv Herb as their primary supplier.
China stands as the global epicentre for the extraction, purification, and semi-synthesis of bile acids. This dominant market positioning is supported by three primary pillars: 原料保障 (Raw Material Security), 规模化制造 (Scale-Up Efficiency), and 先进工艺技术 (Advanced Extraction Process Technologies).
At Chenlv Herb, located in Chengdu, Sichuan, we leverage China's vast agricultural and animal husbandry processing networks. This geographical advantage ensures a consistent, traceable supply of high-grade raw bovine and porcine bile. Our 2,711-square-meter facility features automated extraction reactors, multi-stage crystallization systems, and high-resolution analytical labs (HPLC, GC, MS) to ensure every batch of Cholic Acid or Sodium Deoxycholate meets international pharmacopoeia standards.
Furthermore, our production processes minimize solvent use through closed-loop recycling loops, significantly reducing manufacturing costs while complying with strict green manufacturing mandates. By integrating raw bile collection, primary extraction, and customized synthesis, Chenlv Herb offers a resilient, cost-effective, and highly reliable supply chain to global pharmaceutical, veterinary, and dietary supplement brands.
Discover how the unique biochemical properties of our Cholic Acid derivatives serve key industries globally.
Chenlv Herb provides one-stop contract manufacturing, synthesis, and purification services tailored to your exact criteria.
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We consult with clients to align on project requirements, purity targets, and documentation needs.
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We provide a formal business and technical proposal based on the agreed specifications.
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We finalize the agreement details, confidentiality guidelines, and timelines.
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Our pilot laboratory synthesizes high-grade initial batches and control standards.
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Once samples are approved, our facility initiates the scheduled commercial run.
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Every batch undergoes testing (assay, heavy metals, residual solvents) before generating a COA.
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Finished goods are dispatched via temperature-regulated logistics partners.
Our production facilities operate under strict compliance protocols and hold recognized certifications.
The regulatory framework surrounding bile acid derivatives is shifting toward higher quality control, lower microbial thresholds, and strict limits on related substances. In North America and Europe, researchers focusing on neuroprotection are investigating Tauroursodeoxycholic Acid (TUDCA) for its ability to mitigate endoplasmic reticulum stress, positioning it as a key candidate for neurodegenerative disease pipelines.
Simultaneously, the demand for non-animal-derived starting materials is growing. While synthetic biology remains in its early stages for large-scale production, chemical derivation from sustainable livestock sources remains the most economically viable path. This highlights the importance of partnering with suppliers that maintain comprehensive microbiological audits, viral clearance validations, and BSE/TSE-free certification.
For strategic procurement managers, maintaining a reliable supply chain requires assessing manufacturers on process reproducibility, analytical capabilities (such as heavy metal profiling and organic impurity tracking), and regulatory support (like DMF filings). Choosing an experienced partner like Chenlv Herb, with established compliance records, ensures project safety and long-term continuity.
Stay informed on market dynamics, upcoming conferences, and technical updates from the botanical and biochemical sectors.
Recently, the market price of Citrus aurantium raw materials in China has risen, drawing significant industry attention. As the new production season concludes, price dynamics remain a focal point.
We cordially invite industry partners to join us at CPHI China 2025, where we will showcase our latest advancements in natural plant extraction and high-purity bile acid derivatives.
Explore our custom synthesis solutions and standard chemical portfolios at the upcoming API China conference, a key gathering for raw materials and biotechnology.
Technical guidance on Cholic Acid derivative specifications, procurement parameters, and manufacturing compliance.
Explore further pharmaceutical-grade salts and specialized custom formulations available for wholesale distribution.
