ODM Elevated T Bili Factories & Pricelist

High-Purity Phytochemicals & Bile Acids Addressing Elevated Total Bilirubin Pathways globally

About Us

Chengdu Chenlv Herb Co., Ltd.

Chengdu ChenLv Herb Co.,Ltd. (referred to as "Chenlv Herb") was established in 2012 as a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts and natural pharmaceutical ingredients. Committed to providing high-purity, highly active, and premium-quality natural raw materials, the company serves diverse industries, including pharmaceuticals, health supplements, food, and cosmetics.

Leveraging advanced isolation technologies and rigorous quality validation, our manufacturing matrices support global distributors looking for cost-competitive, pharmacopoeia-compliant bile derivatives and botanical therapeutics designed to restore hepatobiliary balance.

8+
Years of Production
2711㎡
Factory Area
3+
Company Personnel
10+
Products Offered
17+
Cooperative Clients
1+
Countries Served

2012

Established In

Clinical Overview: Physiological Pathways of Elevated Total Bilirubin (T Bili)

Elevated Total Bilirubin (T Bili)—clinically presenting as hyperbilirubinemia—acts as a primary indicator of hepatic clearance dysfunction, bile duct obstruction, or erythrocyte turnover imbalances. Under homeostatic states, bilirubin, an end product of heme catabolism, is conjugated in the liver via uridine diphosphate glucuronosyltransferase (UGT1A1) and excreted into the duodenum via the bile duct.

When biliary dynamics are disrupted, conjugated or unconjugated bilirubin builds up in the plasma. This process requires targeted therapeutic strategies. High-capacity ODM factories like Chengdu Chenlv Herb specialize in developing natural botanical agents and bile acid derivatives to support this physiological pathway:

  • Biliary Excretion Promoters (Choleretics): Bile acids like Chenodeoxycholic Acid (CDCA) and Dehydrocholic Acid actively stimulate bile flow by activating the Farnesoid X Receptor (FXR). This action promotes the clear passage of bilirubin through the hepatic canaliculi.
  • Hepatoprotective Glucuronidation Catalysts: Compounds such as Dipotassium Glycyrrhizinate and Curcumin help mitigate inflammatory liver injury, which in turn preserves hepatocytes and helps restore conjugation kinetics.
  • Enterohepatic Recirculation Blockers: Soluble fibers and botanical binders work to trap free bilirubin in the gastrointestinal tract, preventing its reabsorption and lowering systemic T Bili levels.

The Global B2B Procurement Landscape for T Bili Regulation Agents

Global pharmaceutical companies and health brand developers are shifting away from synthetic treatments in favor of standardized bio-derived active ingredients. This trend is driven by consumer demand for natural health products. B2B procurement professionals must balance several key priorities when sourcing these raw materials:

First, supply chain stability is critical. Chengdu Chenlv Herb's 2711㎡ facility ensures consistent raw material sourcing, reducing risks from seasonal plant supply fluctuations. Second, exact purity requirements are essential. High-performance liquid chromatography (HPLC) is used to verify the precise active compound concentration in each batch, meeting strict international pharmacopoeia standards.

Additionally, pricing remains a key factor. ODM factories provide flexible pricing based on batch sizes, helping buyers manage costs while maintaining high quality standards.

Our Advantages

Choose Chenlv Herb for products that deliver beyond expectations

INNOVATIVE Innovative Icon
Creative designs that elevate your brand. Custom active formulations and specialized extraction procedures designed for maximum therapeutic performance.
High Efficiency Efficiency Icon
Eco-friendly packaging aligned with today's values. Fast lead times combined with modern green solvent recovery systems.
SUSTAINABLE Sustainability Icon
End-to-end clean extraction and packaging solutions. We utilize environmentally friendly extraction technologies that minimize carbon footprints.
SERVICE Service Icon
Fast turnaround to meet your production timelines. Professional customer support representatives are available around the clock to address technical issues.
Quality Assurance Quality Icon
A dedicated QA and QC team supporting you at every stage, conducting full-batch testing from raw botanicals to the final powdered extracts.
Enrich Experience Experience Icon
Years of deep manufacturing expertise. We deliver precision botanical extracts, complex bile acid syntheses, and custom formulation solutions.
Production Advantage Diagram

Customization Process

Chenlv Herb provides one-stop contract manufacturing services.

01
Cooperation Intention

Cooperation Intention

Initial consultations to define specific active ingredients, target specifications, and required purity standards.

02
Quotation

Quotation

We provide a comprehensive pricing structure based on current market costs, required purity levels, and raw material sourcing.

03
Sign Contract

Sign the Contract

Formalizing partnership terms, including quality guarantees, supply agreements, and lead times.

04
Demand Customization

Demand Customization

Developing lab-scale samples and prototypes to verify key technical specifications before full-scale production begins.

05
Volume Production

Volume Production

Scaling up manufacturing under GMP-compliant conditions, utilizing automated extraction and purification lines.

06
Inspection

Inspection

A rigorous quality control protocol testing for heavy metals, solvent residue, microbiology, and active ingredient potency.

07
Shipment

Shipment From the Factory

Secure, temperature-regulated logistics handling to deliver protected ingredients directly to your storage facility.

Global Regulatory Standards and Quality Compliance

The production of active compounds for metabolic and hepatic products is subject to strict regulatory oversight worldwide. Regulatory bodies such as the US FDA, EFSA, and NMPA require high traceability and strict control over processing residues.

Our manufacturing processes comply with key global standards, including ISO 9001:2015, ISO 22000, and GMP guidelines. Our bile acid products, such as Chenodeoxycholic Acid, undergo gas chromatography-mass spectrometry (GC-MS) analysis to confirm the absence of animal pathogens or toxic impurities. Additionally, our botanical extracts are certified Halal and Kosher, meeting diverse market requirements.

Every shipment is accompanied by a comprehensive Certificate of Analysis (COA), reflecting raw material testing, heavy metal metrics (such as Lead, Arsenic, and Cadmium), and microbial load limits. This documentation ensures seamless compliance clearance at international borders.

Future Outlook: Advanced Extraction Technologies

Modern phytomedicine requires higher bioavailability and cleaner extraction technologies. Our R&D team is focused on implementing supercritical carbon dioxide extraction methods, which eliminate the need for traditional organic solvents. This approach delivers highly concentrated, clean active compounds.

We are also investigating micro-encapsulation techniques. By coating sensitive molecules, such as Curcumin or Hesperidin, we can protect them through the gastric tract. This targeted delivery method increases absorption rates in the small intestine, enhancing their therapeutic effect in support of biliary health.

Application Areas

Developing raw materials that support human health, cosmetics, and animal nutrition.

Health Care

Health Care

Driven by the concept of "homology of medicine and food" and modern health needs, plant extracts have gradually become the core raw materials for the development of health care products due to their natural, green and safe characteristics.

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Pharmaceutical

Pharmaceutical

From herbal formulas recorded in ancient books to modern innovative drugs, plant extracts occupy the prominent position in the pharmaceutical industry due to their natural active ingredients and unique pharmacological effects.

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Cosmetics

Cosmetics

With consumers' pursuit of natural, safe, and sustainable skincare concepts, plant extracts have become a new favorite in the cosmetics industry due to their mildness, versatility, and biocompatibility, bringing new solutions for skin care.

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Animal Nutrition

Animal Nutrition

Plant extracts have shown great potential in improving animal health, enhancing production performance and optimizing culture benefits, and are gradually becoming a research hotspot and new favorite in the field of animal nutrition.

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Certificate Display

Our company is certified by ISO9001, ISO22000, HALAL, KOSHER and FDA etc.

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Certificate 3
Certificate 4
Certificate 5
Certificate 6

Latest News

We integrated research and development, manufacturing and sales together.

Citrus aurantium price trend

The price of Citrus aurantium raw material rises, what is the market prospect of extract?

Recently, the market price of Citrus aurantium raw materials in China has been on the rise, drawing significant attention from the industry. As the new production season comes to an end and new supplies enter the market, price fluctuations have become a focal point.

READ MORE May 28, 2025
CPHI China Exhibition

Chengdu Chenlv Herb sincerely invites colleagues in the industry to explore new opportunities of plant extraction at 2025 CPHI China

As a 'calling card' for leading China's pharmaceutical industry onto the global stage, the 23rd China Pharmaceutical Raw Materials Exhibition (CPHI China 2025) will join hands with the 18th China Pharmaceutical Machinery.

READ MORE May 28, 2025
API Conference invitation

Chengdu ChenLv Herb sincerely invites you to attend the 92nd API conference and start a new chapter of biotechnology together

Join Chengdu Chenlv Herb at the 92nd API Conference, where we will present our latest active ingredients and manufacturing capabilities, fostering partnerships that advance global health standards.

READ MORE May 28, 2025

Frequently Asked Questions (FAQ)

Answers to common questions regarding our manufacturing processes, certifications, and support services.

Q1: How do bile acids like Chenodeoxycholic Acid manage elevated T Bili?

Bile acids serve as signaling molecules that activate the Farnesoid X Receptor (FXR) and stimulate hepatobiliary secretion, promoting the safe transit and excretion of accumulated bilirubin from the liver.

Q2: What is the typical lead time for custom ODM orders?

Standard customized formulations require 2–3 weeks for lab sample development and validation. Bulk manufacturing runs are generally completed and shipped within 30 to 45 days after sample approval.

Q3: How does Chenlv Herb guarantee the quality of its bile products?

We use HPLC verification, gas chromatography, and atomic absorption spectroscopy to ensure raw materials are free of heavy metals, pesticide residues, and harmful pathogens, complying with USP/EP standards.

Q4: Are your manufacturing processes environmentally friendly?

Yes, we prioritize green chemistry. We integrate solvent recycling systems and eco-friendly packaging processes to minimize environmental impacts throughout our operations.

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