High-purity bile acid derivatives, pharmaceutical-grade TUDCA, UDCA, and Sodium Deoxycholate engineered for Tokyo's leading clinical development, diagnostic laboratories, and advanced biopharma formulations.
Providing the medical hubs and research facilities in the Tokyo metropolitan area with validated, pure cholic acid active ingredients.
Pure cholesterol carrier molecules customized for lipid nanoparticle (LNP) drug delivery systems.
For high-accuracy in-vitro diagnostics (IVD) assays and liver function calibration standards.
Base raw material for synthetic drug modifications and complex micellar emulsion agents.
High-efficacy active ingredient used widely in gallstone dissolution and metabolic pathway studies.
Tokyo is the heart of Japanese life sciences, containing major pharmaceutical research corridors such as Nihonbashi and Science Parks in Kawasaki. The city's biotechnology clusters show growing demand for cholic acid derivatives. Cholic acid is the parent molecule to various bile salts that are essential in clinical development, drug solubility, and biochemical diagnostics. Local R&D complexes demand highly stable, documented (PMDA and DMF certified) sources of raw active pharmaceutical ingredients (APIs).
Global supply chain volatility has pushed Tokyo's procurement managers to prioritize raw materials that boast strong certification portfolios, biological safety compliance (specifically TSE/BSE-free clearances), and stable cost models. This matches perfectly with Chenlv Herb's optimized industrial-scale extraction and synthesis processes.
Established in 2012, Chengdu Chenlv Herb Co., Ltd. (referred to as "Chenlv Herb") is a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts, custom bile acid products, and natural pharmaceutical ingredients. We operate with strict focus on high-purity, highly active, and premium-quality natural raw materials designed to feed global industries including pharmaceuticals, health supplements, functional food, and cosmetics.
With our modern facilities based in Chengdu, China, we bridge the gap between heavy primary supply chains and local scientific demands in international hubs like Tokyo, providing custom synthesis and swift distribution.
Our facilities run under state-of-the-art parameters to ensure reproducibility, quality validation, and supply security for our partners worldwide.
Advancing bile acid chemistry from raw animal precursors to targeted, bio-identical synthetic structures.
Historically, cholic acid extraction was heavily dependent on manual processing of bovine or porcine bile fractions. Modern biotechnology has transitioned towards refined crystallization and biocatalytic pathways. Chenlv Herb utilizes clean extraction methods, removing impurities such as unwanted lipids, biological residues, and pigments. This results in cholic acid derivatives with a minimum purity of 98% to 99% by HPLC.
Our research team focuses on biocatalytic conversion, specifically optimizing the production of UDCA and TUDCA. By using specific enzymatic steps, we convert primary bile acids into targeted metabolites. This method reduces organic solvent waste, providing the high-purity profile that Japanese PMDA standards require.
Technical Focus: By utilizing high-resolution crystallization columns and automated temperature feedback systems, we control the polymorphic forms of sodium deoxycholate and dehydrocholic acid. This ensures uniform dissolution rates when utilized in cell-lysis formulations and pharmaceutical manufacturing.
| Product Compound Name | Primary Bio-Function / Application | Standard Purity (HPLC) | Typical Physical Appearance | Key Quality Parameters |
|---|---|---|---|---|
| Cholic Acid | API Precursor, Emulsification, Cell Lysis Research | ≥ 98.0% | White crystalline powder | Heavy metals ≤ 10 ppm, Loss on drying ≤ 1.0% |
| Ursodeoxycholic Acid (UDCA) | Gallstone dissolution, hepatoprotective treatments | ≥ 99.0% | Fine white powder | TSE/BSE free certified, Residual solvents USP compliance |
| Tauroursodeoxycholic Acid (TUDCA) | Mitochondrial stabilizer, neuroprotective studies | ≥ 98.5% | Off-white to white crystalline | High water solubility, Endotoxin validated |
| Sodium Deoxycholate | Detergent for membrane protein extraction | ≥ 99.0% | Hygroscopic white powder | Clear colorless solution in water, low UV absorbance |
Our commitment to consistent biochemical quality, reliability, and service helps drive global manufacturing forward.
We develop customized synthesis routes and biochemical modifications to match specialized application requirements.
Automated manufacturing pathways ensure fast lead times, consistent batch-to-batch quality, and stable delivery timelines.
Our processes focus on green chemistry, using recycled solvents, minimized effluents, and clean animal-source logistics.
Comprehensive support from early-stage chemical design through large-scale industrial bulk shipping.
We run standard HPLC, ICP-MS, and GC tests for every batch, offering transparent certificates of analysis (CoA).
Over a decade of biochemical engineering expertise ensures we can solve complex solubility and conjugation challenges.
Customized bile acid derivatives designed to solve functional challenges across diverse biological disciplines.
Meeting dietary requirements with high-grade cholic derivatives that support lipid metabolism and liver function formulations.
Read More
High-purity APIs (UDCA, TUDCA) designed for pharmaceutical research and cell-protective drug manufacturing.
Read More
Sodium deoxycholate used as an emulsion stabilizer and functional fat-dissolving research component.
Read More
Using bile acid fractions to support digestion, feed utilization, and general animal gut health.
Read MoreFrom initial design through mass production, we provide full transparency and reliable service at each stage.
Our team works with your technical department to define purity, solubility, and regulatory requirements.
We provide a clear cost proposal, including shipping options to Tokyo Bay or direct-to-lab courier delivery.
We formalize our partnership terms, including quality guarantees, delivery timelines, and regulatory support documentation.
We supply pilot-scale samples for in-house laboratory trials and HPLC testing.
Our facility schedules and runs the production campaign, applying strict in-process controls.
Our quality department runs final analysis and issues the Certificate of Analysis (CoA) and matching spectral charts.
Safely packaged, temperature-monitored products are shipped directly to your designated manufacturing site or lab.
As regulatory requirements become stricter, Chenlv Herb has upgraded its production lines to leverage Industry 4.0 automation. By utilizing automated reactors, real-time crystallization control, and inline analytical tools (PAT), we minimize human error and batch-to-batch variation.
Our location in Sichuan, China provides direct access to high-quality raw materials and efficient transport infrastructure. This allows us to offer competitive pricing without compromising quality. Combined with reliable shipping lines directly to Tokyo Bay ports, we ensure a stable supply of materials for your production schedule.
Our operations follow strict regulatory requirements to ensure full safety and complete documentation.
Stay informed with technical news and biochemical analysis regarding cholic acid derivatives.
An in-depth look at how raw material supply fluctuations shape prices for natural extracts and bio-acids, and tips on managing procurement risk.
Join us at CPHI China to discuss customized synthesis options for high-purity sodium deoxycholate and therapeutic bile acid compounds.
A technical guide detailing how PMDA and USP compliance shapes testing requirements for importing high-purity active ingredients into Asian markets.
Answering key regulatory and manufacturing questions for cholic acid procurement.
We work with fully audited animal sourcing chains. Each batch is accompanied by complete veterinary certifications and declaration documents to ensure full tracebility and compliance for medical and laboratory applications.
Standard catalog products are shipped from inventory within 3 to 5 business days. Custom synthesis or specific micronization processes generally require 3 to 5 weeks, depending on target metrics and validation protocols.
Yes. We provide complete technical packages, including raw material source logs, residual solvent profiles (USP <467>), and heavy metal validation data to support your regulatory approval processes.
We offer flexible commercial terms for qualified customers, including standard wire transfers, L/C payment structures, and annual supply agreements to secure stable pricing.
Premium raw materials and APIs engineered to international pharmaceutical and biological laboratory requirements.
Naturally sourced dry extract designed for microbiological culture media preparations.
Pure conjugated bile salt for lipid-transport and metabolic pathway studies.
Highly soluble sodium salt optimized for cell culture studies and in-vitro testing.
Validated raw material used in neuroprotective and protein-folding research.
Providing steady supply lines for manufacturing hepatoprotective supplement brands.
Validated batch production matching EU standards for import and research safety.
Customized moisture profiles and particle-size milling for specific client requirements.
Synthesized under GMP guidelines to ensure minimal organic solvent residues.
Highly pure sodium salts optimized for biological assays and diagnostic reagent formulations.
High-grade surfactant used for cellular lipid bilayer breakdown and extraction workflows.
Key detergent component used in standard RIPA lysis buffer formulations.
High-purity therapeutic agent for gallstone dissolution and clinical drug development.
Get in touch with our technical sales team for pricing, detailed product specifications, and regulatory documentation for Tokyo or your local manufacturing hubs.