High-purity bile acid standards, biological extracts, and customized synthesis platforms for Berlin’s pharmaceutical research centers and industrial drug development pipelines.
Established in 2012, Chengdu Chenlv Herb Co., Ltd. is a premier high-tech enterprise specialized in the R&D, industrial-scale production, and global export of high-purity botanical extracts, bile acid derivatives, and natural pharmaceutical active ingredients (APIs).
With an advanced manufacturing plant covering 2,711㎡, we leverage cutting-edge separation technology, crystallization systems, and rigorous analytical tools to support life science sectors. Over the past 8+ years, our facilities have delivered highly stable, biologically active raw materials compliant with international pharmacopoeias (USP, EP, JP).
We work closely with global pharmaceutical formulators, diagnostic kit builders, and veterinary science hubs to bridge the gap between traditional extraction and high-end biotechnology, optimizing therapeutic bioavailability across diverse target segments.
The Berlin-Brandenburg region stands as one of Europe’s most dense biomedical clusters, housing renowned research institutes (like Charité - Universitätsmedizin Berlin), innovative biotech startups, and large-scale contract research organizations (CROs). The local bio-pharmaceutical landscape has shown an expanding reliance on standardized bile acid derivatives—specifically primary and conjugated cholic acids—to drive clinical pipelines focused on metabolic syndromes, hepatic dysfunction, and lipid transport mechanisms.
Furthermore, as a leading center for drug delivery technology, Berlin's academic and commercial labs are actively exploiting the amphiphilic properties of Cholic Acid series products. These compounds act as biological permeation enhancers, aiding in the formulation of polymeric micelles, liposomal carriers, and targeted drug delivery vectors that can penetrate the blood-brain barrier or improve oral absorption rates of challenging therapeutic agents.
To meet the strict standards of Germany's pharmaceutical industry (governed by the BfArM and EMA guidelines), local developers require raw materials with absolute structural consistency, batch-to-batch repeatability, and comprehensive chromatographic documentation (HPLC-ELSD/CAD profiles).
How Chengdu Chenlv Herb achieves pharmaceutical-grade refining and absolute structural characterization for European pharmaceutical enterprises.
We employ biotransformation and semi-synthetic pathways derived from highly controlled animal resources. By optimizing biological extraction with highly specific enzymatic steps, we avoid organic trace residues, ensuring low environmental impact and clean chemical profiles.
Our advanced crystallization units maintain precise control over cooling rates, solvents, and agitation profiles. This ensures that polymorphs, particle size distributions (PSD), and bulk density strictly match customer specifications for downstream wet-granulation or direct compression processes.
Every industrial batch undergoes HPLC-ELSD (High-Performance Liquid Chromatography coupled with Evaporative Light Scattering Detection) and gas chromatography mass spectrometry (GC-MS) validation, ensuring total impurities remain below 1.0% with undetectable limits of biological contaminants.
As a global API exporter, Chenlv Herb has transitioned to Smart Factory 4.0 standards. Our production lines integrate DCS automated control systems that monitor and adjust crucial parameters (temperature, pH, solvent concentration) in real-time, minimizing human error and ensuring complete traceability.
Our location in Chengdu, Sichuan, provides us with stable access to upstream starting materials and highly developed logistics routes. This geographic benefit, combined with our large-scale processing capacity, allows us to maintain stable pricing and mitigate market volatility. Berlin clients receive dependable, year-round cargo supply with no production downtime.
In addition, our site operations follow strict ESG (Environmental, Social, and Governance) principles. By operating closed-loop solvent recovery units and biological waste treatment facilities, we lower the carbon footprint of our operations, helping European clients meet their corporate sustainability targets.
Choose Chenlv Herb for raw materials and services that deliver beyond industrial expectations.
Advanced purification systems and chemical optimization to elevate standard formulations and support complex R&D projects.
Optimized manufacturing timelines, quick custom processing, and efficient global distribution channels.
Environmentally conscious chemical extraction, efficient resource recycling, and low carbon footprint practices.
Rapid dispatch, responsive communication, and tailored logistics solutions aligned with your schedule.
Dedicated quality control technicians monitoring every step from raw bile collection to final shipping container inspection.
Over a decade of industry expertise ensuring precise synthesis and regulatory compliance across diverse biological sectors.
Industrial bile acids and cholic derivatives play key roles across human health, pharmaceutical research, skincare science, and veterinary nutrition.
Driven by modern wellness trends, natural bile extracts serve as active raw materials in digestive wellness, supporting natural fat absorption and lipid metabolism.
From ancient phytotherapy to modern drug formulations, cholic acid derivatives play key roles in developing therapies for liver diseases, cholestasis, and advanced drug delivery carriers.
With growing interest in biocompatible formulations, highly purified deoxycholic compounds assist in lipolytic systems and emulsified skincare formulations.
Bile acids show high efficacy in optimizing fat absorption in livestock and aquaculture systems, enhancing feed efficiency and metabolic performance.
Providing comprehensive, one-stop contract manufacturing and supply solutions from molecular specification design to global delivery.
Initial technical consultation to define required assay limits, crystal form, and compliance standards.
Detailed technical proposal, pricing structure, and target timeline verification.
Establish production contracts, quality agreements, and regulatory filing schedules.
Synthesize lab-scale samples for customer laboratory verification and analytical testing.
Scale-up production in our GMP-compliant facility using automated process controls.
Final batch analytical validation, testing for heavy metals, microbial limits, and issuance of CoA.
Export clearance, secure packaging, and temperature-monitored shipment to your facility in Berlin or international destinations.
Navigating BfArM, EMA, and EDQM requirements with complete regulatory documentation.
Entering the European and German drug supply chains requires strict adherence to regulatory standards. Chenlv Herb ensures that our entire Cholic Acid series complies with the European Pharmacopoeia (EP) monographs. We supply our clients with comprehensive Chemistry, Manufacturing, and Controls (CMC) dossiers to facilitate smooth regulatory approvals.
Full biological safety certification showing complete traceability of starting materials, in line with EMA/410/01 guidance on minimizing transmissible spongiform encephalopathy risks.
Active Substance Master Files (ASMF) are available for regulatory submission, supporting product registration with European regulatory authorities.
Detailed analysis of organic impurities, heavy metals, and residual solvents in compliance with ICH Q3A and Q3C guidelines.
Our plant operations and management systems are fully certified by ISO9001, ISO22000, HALAL, KOSHER, and FDA registrations.
Stay informed on phytomedicine research, raw material supply dynamics, and bio-industrial exhibitions.
Recently, the market price of Citrus aurantium raw materials in China has risen, drawing industry attention. As the new harvest season draws to a close, supply dynamics and processing costs remain key factors for formulation planning.
Join us at CPHI China 2025 to discuss key trends in bile acid synthesis, phytochemistry, and international trade channels.
Discover our latest production scale-ups, custom synthesis offerings, and high-purity biological derivatives at China's leading API showcase.
Key answers regarding chemistry, documentation support, and procurement channels for the Berlin market.
We supply Cholic Acid with assay levels of ≥98.0% and ≥99.0% by HPLC. For biological applications, we strictly manage microbial counts, bacterial endotoxins, and heavy metal concentrations (typically under 10 ppm) to ensure compliance with pharmaceutical standards.
We source our raw animal materials exclusively from certified facilities under veterinary supervision. We supply full trace certificates, country-of-origin documentation, and veterinary health records alongside our BSE/TSE-free statements, in line with EMA regulations.
Yes. Our engineering facilities support tailored micronization, allowing us to supply target particle size distributions (D50, D90) to meet your formulation needs. We also provide custom crystallization to produce specific polymorphs.
Standard stock items can be dispatched within 3–5 working days. For bulk customization or specialized synthesis, standard production times range from 3 to 6 weeks, followed by dynamic logistics arrangements by air or sea to Frankfurt or Berlin terminals.
Yes, we can supply pilot-batch samples (10g to 500g) along with their corresponding Certificates of Analysis (CoA) and MSDS documentation for validation testing in your facility.
Our plants operate under ISO9001 and ISO22000 quality management systems. We welcome third-party audits and offer technical support to help you prepare your regulatory submissions.
Explore our range of primary bile acids, conjugated salts, and high-purity derivatives.
