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Rotundine (CAS: 10097-84-4) is a tetrahydroisoquinoline alkaloid extracted from the roots of Stephania sinica (a member of the Menispermaceae family). As a natural medicine ingredient independently developed in China, it has dual analgesic and sedative effects, and is non addictive, widely used in the treatment of chronic pain and insomnia. In 2020, it was included in the list of urgently needed overseas new drugs in the Chinese Pharmacopoeia.

Product Name: Rotundine

IUPAC Name: (6S,12aR)-2,3,6,7,12,12a-Hexahydro-6-methyl-1H-[1,3]dioxolo[4',5':4,5]benzo[1,2-b]quinolizin-10-ol

CAS No.​: 10097-84-4

Molecular Formula: C₂₁H₂₅NO₄

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