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ODM Diosmin Pricelist, Quotes

Diosmin (CAS: 520-27-4) is a flavonoid compound derived from Rutaceae plants, it exerts therapeutic effects through multiple mechanisms: enhancing venous tone (reducing capillary permeability by 30%), inhibiting inflammatory cytokines (decreasing TNF-α and IL-6 secretion), and providing antioxidant activity (free radical scavenging capacity twice that of vitamin E). Clinically, it is primarily used to treat chronic venous insufficiency (daily dose 500-1000mg), acute hemorrhoidal episodes, and post-surgical lymphedema, and is classified by the European Medicines Agency (EMA) as the first-line venoactive drug. Modern formulations utilize micronization technology to achieve 3-fold higher bioavailability compared to non-micronized preparations, with further absorption optimization possible through phospholipid complexation.

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