Explore our primary botanical active compounds refined using advanced Factory 4.0 standards. Essential solutions for hepatic, metabolic, and systemic health therapeutics.
In clinical medicine and traditional ethnopharmacology, the term "Black Jaundice" refers to the severe, chronic manifestations of icterus, typically triggered by extreme hyperbilirubinemia, hepatocellular destruction, or complete mechanical bile duct obstruction. Unlike simple neonatal jaundice, severe adult cholestatic jaundice presents with dark pigmentation due to excessive systemic oxidation of accumulated bilirubin metabolites. Modern clinical interventions require highly purified natural components capable of regulating bilirubin pathways, promoting bile acid circulation, and protecting hepatic tissue from oxidative cell death.
Direct therapeutic formulations targeting cholestasis utilize high-purity exogenous Bilirubin and bile acid derivatives such as Tauroursodeoxycholic acid (TUDCA). Exogenous bilirubin acts as a potent endogenous cytoprotective antioxidant at controlled concentrations, while TUDCA relieves endoplasmic reticulum (ER) stress in hepatocytes, promoting healthy bile acid conjugation and preventing hepatocytic apoptosis.
Indirubin, the active bis-indole pigment derived from traditional indigo-yielding plants, is globally recognized for its anti-inflammatory and anti-proliferative activities. Clinically, it acts as a selective inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 beta (GSK-3β). It is a vital raw material for compounding agents that mitigate hepatosplenomegaly associated with severe jaundice.
As a synthetic/semi-synthetic derivative of cholic acid, Sodium Dehydrocholate serves as an aggressive hydrocholeretic agent. By increasing the volume of thin, low-viscosity bile secretion, it effectively flushes biliary obstructions, alleviating severe accumulation of bilirubin pigment that leads to systemic darkening and liver congestion.
Chengdu Chenlv Herb integrates these highly specific biochemical agents (Bilirubin, Indirubin, TUDCA, and Sodium Dehydrocholate) alongside metabolic drivers like Dihydroberberine and protective flavonoids like Hesperidin Methyl Chalcone to offer comprehensive formulation options for pharmaceutical manufacturers globally.
Chengdu Chenlv Herb's R&D department operates at the frontier of botanical separation science. Over the next decade, our technical roadmap focuses on transition from classical organic extraction to advanced green chemistry principles and synthetic biology.
Our strategic focus centers on scaling multi-stage molecular distillation, enzymatic bioconversion of bile acids, and high-performance chromatography. Through these innovations, we achieve purities of up to 99.8% for compound extracts while virtually eliminating organic solvent residues, meeting strict European and US Pharmacopoeia standards.
Chengdu Chenlv Herb Co., Ltd.
Established in Chengdu, Sichuan, we leverage rich local botanical reserves and advanced local science hubs to engineer premier active ingredients for global pharmaceuticals, dietary supplements, food, and cosmetic industries.
Providing reliable global supply security through automated processes and real-time analytical control.
Our Chengdu extraction facility uses IoT-enabled control loops, monitoring temperature, pressure, and solvent flow dynamically. This guarantees maximum active constituent retention and complete batch-to-batch uniformity.
Each batch undergoes strict testing via High-Performance Liquid Chromatography (HPLC) and Gas Chromatography-Mass Spectrometry (GC-MS). We ensure zero contaminants, heavy metal clearance, and precise potency verification.
Backed by secure raw material sourcing regions across China and streamlined logistics pipelines, we insulate global procurers from raw material supply shocks, offering stable year-round price structures.
Choose Chenlv Herb for products that deliver beyond expectations
Creative designs and novel extraction solutions that elevate your brand.
Eco-friendly packaging and optimized separation methods aligned with today's values.
End-to-end cosmetic and pharmaceutical raw material solutions with minimal environmental footprint.
Fast turnaround and streamlined global logistics to meet your tight production timelines.
A dedicated quality control team supporting you with analytical documentation every step of the way.
Years of industrial expertise ensuring formulation precision, regulatory documentation, and manufacturing excellence.
Targeted botanical extracts optimized for specialized clinical and dietary fields.
Driven by the concept of "homology of medicine and food" and modern health needs, plant extracts have gradually become the core raw materials for the development of health care products due to their natural, green and safe characteristics.
From herbal formulas recorded in ancient books to modern innovative drugs, plant extracts occupy the prominent position in the pharmaceutical industry due to their natural active ingredients and unique pharmacological effects.
With consumers' pursuit of natural, safe, and sustainable skincare concepts, plant extracts have become a new favorite in the cosmetics industry due to their mildness, versatility, and biocompatibility, bringing new solutions for skin care.
Plant extracts have shown great potential in improving animal health, enhancing production performance and optimizing culture benefits, and are gradually becoming a research hotspot and new favorite in the field of animal nutrition.
Chengdu Chenlv Herb provides professional, transparent, and compliant contract manufacturing services.
Determine product specifications & requirements.
Provide transparent proposal & pricing structures.
Discuss legal details & finalize agreements.
R&D lab processes pilot sample extraction.
Scheduled production post-sample confirmation.
Issuing analytical certificate (COA) per batch.
Deliver finalized premium products safely.
Ensuring our systems and materials comply with strict global safety protocols including ISO9001, ISO22000, HALAL, KOSHER, and US FDA requirements.
Modern international pharmaceutical houses require deep supply chain integration. We do not just supply raw compounds; we design functional ingredient profiles tailored to specific biological targets. For enterprises addressing cholestatic conditions, metabolic syndromes, or inflammatory cascades, we offer custom blending, granularization, and micro-encapsulation to facilitate processing in tablet, softgel, or liquid matrixes.
Our regulatory support infrastructure includes complete Drug Master File (DMF) capability, stability testing studies matching ICH guidelines, and complete traceability from botanical origin to dispatch. This streamlines validation tasks for quality assurance directors and regulatory affairs divisions operating under strict oversight.
Stay informed on scientific advancements, exhibition schedules, and material market trends.
As the primary production season draws to an end, shifts in crop yields shape pricing structures and output strategies for critical flavonoids.
Join our formulation chemists in Shanghai to explore advanced extraction developments and secure custom contracts.
Discover our high-purity bile acid lines and functional active ingredients designed to address metabolic and liver conditions.
Answering critical queries from formulation scientists and purchasing executives.
High-purity flavonoids, alkaloids, and enzymes designed to stabilize formulations and support patient recovery.
