CE Certification Actase Lutein Za Manufacturer & Manufacturers

Premium Medical-Grade Macular Carotenoids (Lutein, Zeaxanthin & Meso-Zeaxanthin) for Advanced Eye Health Applications

Understanding Actase Lutein Za: The Clinical Gold Standard in Macular Carotenoid Formulations

Actase Lutein Za represents a major leap forward in targeted ophthalmic nutrition. It is designed to mimic the natural composition of the human macular pigment. The macular pigment is situated in the central region of the retina, called the macula lutea. This area is responsible for high-acuity, sharp, and detailed vision. Clinical investigations have confirmed that the macular pigment is composed of three dietary carotenoids: Lutein, Zeaxanthin, and Meso-Zeaxanthin. The synergistic ratio of these three pigments functions as a "natural blue-light filter," absorbing damaging shortwave light radiation and mitigating local oxidative stress.

As a CE certified Actase Lutein Za manufacturer, we focus on delivering raw material configurations that meet strict European Union safety and efficacy standards. CE Certification validates that our ophthalmic-grade raw materials satisfy the essential health, safety, and environmental protection benchmarks. Our advanced production technology isolates, purifies, and stabilizes these macular carotenoids, ensuring optimal bioavailability for downstream formulation.

"Clinical trials such as the Age-Related Eye Disease Study 2 (AREDS2) and the CREST (Central Retinal Enrichment Supplement Trials) have demonstrated that supplementing with the three macular carotenoids (Lutein, Zeaxanthin, and Meso-Zeaxanthin) significantly improves Macular Pigment Optical Density (MPOD) and enhances contrast sensitivity in both healthy individuals and patients suffering from early-stage Age-Related Macular Degeneration (AMD)."

The Role of Meso-Zeaxanthin in Eye Health Formulations

While Lutein and Zeaxanthin are widely found in green leafy vegetables and yellow fruits, Meso-Zeaxanthin is rarely present in the typical human diet. Meso-zeaxanthin is primarily synthesized in the retina from ingested lutein. However, as the human body ages, or due to metabolic imbalances, the enzymatic conversion rate of lutein to meso-zeaxanthin drops significantly. Supplying pre-formed Meso-Zeaxanthin directly through Actase Lutein Za formulations bypasses this metabolic bottleneck.

Our manufacturing facility uses advanced bio-isomerization techniques to convert high-purity lutein extracted from marigold flowers (Tagetes erecta L.) into premium-grade Meso-Zeaxanthin. This allows us to supply the optimal clinical ratio of 10mg Lutein, 10mg Meso-Zeaxanthin, and 2mg Zeaxanthin. This ratio is ideal for maximizing ocular protection and pigment density.

Carotenoid Spec. Source Material Typical Assay Methods Primary Function in Retina
Lutein (Free/Ester) Marigold Flowers (Tagetes erecta) HPLC / UV-Vis Filters peripheral blue light, scavenger of free radicals.
Zeaxanthin Marigold Flowers / Lycium barbarum HPLC Protects mid-peripheral retina, enhances contrast sensitivity.
Meso-Zeaxanthin Synthesized / Bio-isomerized Lutein Chiral-HPLC Dominates the fovea centralis, shields high-acuity photodetectors.

About Us

Chengdu Chenlv Herb Co., Ltd.

Chengdu ChenLv Herb Co.,Ltd. (referred to as "Chenlv Herb") was established in 2012 as a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts and natural pharmaceutical ingredients. Committed to providing high-purity, highly active, and premium-quality natural raw materials, the company serves diverse industries, including pharmaceuticals, health supplements, food, and cosmetics.

We are situated in the center of botanical innovation in Southwest China. Chenlv Herb utilizes state-of-the-art extraction technology and enforces rigorous testing procedures to make sure our products exceed international health and safety regulations.

8+
Years of Production
2711㎡
Factory Area
30+
R&D Experts
100+
Products Offered
170+
Cooperative Clients
30+
Countries served

2012

Established In

Our Core Advantages

Choose Chenlv Herb for products that deliver beyond expectations, built upon a foundation of scientific integrity.

INNOVATIVE Innovative Icon
Creative formulations, modern manufacturing pathways, and custom particle-engineering designs that elevate your brand.
High Efficiency High Efficiency Icon
High-yield solvent extraction systems coupled with eco-friendly practices that align with global green energy values.
SUSTAINABLE Sustainable Icon
End-to-end traceablity protocols, from agricultural marigold fields to the final standardized powder and liquid shipments.
SERVICE Service Icon
Fast response and streamlined custom packaging solutions designed to match your production schedules and launch timelines.
quality assurance Quality Assurance Icon
A dedicated quality management team implementing HPLC, GC, and ICP-MS testing supporting you every step of the way.
Enrich Experience Enrich Experience Icon
Over a decade of manufacturing expertise, delivering precision, reliable consistency, and verified active content assays.

Actase Lutein Za Manufacture: The Strategic Advantages of China-Based Plants

China has become a major global hub for the extraction of carotenoids. This is thanks to natural raw material reserves, integrated industrial supply chains, and advanced engineering technologies. Chengdu Chenlv Herb Co., Ltd. leverages these advantages to offer a stable, high-purity, and cost-effective supply of Actase Lutein Za.

  • Agricultural Feedstock Security: Sichuan province and surrounding areas feature diverse microclimates suitable for marigold cultivation. We manage agricultural partnerships that ensure non-GMO, pesticide-monitored flower harvesting, guaranteeing chemical consistency from the ground up.
  • Advanced Extraction Facilities: Our 2711㎡ facility is equipped with modern extraction units. These include low-temperature vacuum concentrators, supercritical fluid CO2 extractors, and high-efficiency column chromatography systems. This setup prevents thermal degradation of Lutein, Zeaxanthin, and Meso-Zeaxanthin isomers.
  • Scientific Optimization & Stabilization: Carotenoids are highly sensitive to oxygen, light, and heat. Our plant uses microencapsulation technology to produce cold-water-dispersible (CWD) powders, beadlets, and oil suspensions. This protects the active isomers, offering improved stability for tablets, softgels, and hard capsules.
  • Rigorous Cost Controls: We streamline our production from direct raw material sourcing through extraction to automated packaging. This control reduces manufacturing overheads, allowing us to pass the savings on to our global partners without compromising on quality.

Macro Industry Trends: The Shift Toward Triple-Carotenoid Formulations

For years, eye health products relied solely on Lutein. However, recent clinical studies have highlighted the importance of Meso-Zeaxanthin. Modern macular health science shows that Meso-Zeaxanthin is concentrated in the foveal region, which handles central, high-resolution vision. Lutein is found in the peripheral area, and Zeaxanthin occupies the mid-peripheral zone.

Because of this, global brands are shifting from simple lutein formulations to triple-carotenoid combinations. The market for products like Actase Lutein Za is growing. Driving factors include an aging population, rising screen time from digital devices, and a growing consumer focus on proactive, preventive health.

Customization Process

Chenlv Herb provides one-stop contract manufacturing and optimization services for global brands.

Cooperation Intention Icon 01

Cooperation Intention

Communicate with clients to analyze formulation ideas and establish technical product requirements.

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Quotation

Provide a comprehensive project proposal and commercial quote based on production specifications.

Sign the Contract Icon 03

Sign the Contract

Finalize contract terms, establish quality agreements, and define delivery milestones.

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Demand Customization

Synthesize lab-scale pilot samples and run initial purity and stability tests.

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Volume Production

Upon sample approval, schedule large-scale manufacturing at our certified facility.

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Inspection

Conduct chemical assays, microbiological screening, and issue the Certificate of Analysis (CoA).

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Shipment From Factory

Coordinate customs clearance, logistics, and ship final goods with comprehensive compliance documentation.

Certificate Display

Our manufacturing system is certified by ISO9001, ISO22000, HALAL, KOSHER, FDA, and CE compliant standards.

ISO Certification
Halal Certification
Kosher Certification
Quality Standard Certificate
GMP Compliance Doc
Safety Standard Certificate

Localized Application Scenarios for Actase Lutein Za Formulations

For brands seeking market differentiation, Actase Lutein Za can be formulated into a variety of delivery formats:

  • Age-Related Eye Care (AMD Prevention): Designed for senior health lines, softgels combining Actase Lutein Za with omega-3 fatty acids (DHA/EPA), zinc, and copper offer complete macular protection.
  • Digital Screen Defense & Blue Light Filtering: Targeted at young professionals and gamers, clean-label gummies or chewable tablets containing 10mg Lutein, 10mg Meso-zeaxanthin, and 2mg Zeaxanthin help alleviate digital eye strain and dry eye symptoms.
  • Nutricosmetics (Skin Shielding): Ocular carotenoids accumulate in skin tissue, providing systemic defense against UV-induced oxidative damage. Low-dose oral capsules or beauty drinks combine these carotenoids with collagen peptides for dual skin and eye health.

Global Procurement and Quality Assurance Standards

B2B raw material procurement requires strict quality verification. Large international buyers must evaluate several key criteria:

  • Active Assay Validation: Suppliers must confirm carotenoid percentages using validated Chiral-HPLC chromatography, separating Meso-Zeaxanthin from standard Zeaxanthin.
  • Chemical and Bio-contaminant Limits: Products must comply with strict international thresholds for heavy metals (Lead < 3.0 ppm, Cadmium < 1.0 ppm, Mercury < 0.1 ppm), pesticide residues, and microbial activity.
  • Thermal and Oxidative Stability: Because carotenoid powders oxidize easily, suppliers should use nitrogen-purged packaging, vacuum-sealed aluminum containers, and temperature-controlled shipping to preserve product potency.

Latest Industrial News & Events

Keep track of our technological innovations, upcoming trade conferences, and raw material market trends.

Citrus aurantium raw material news

Raw Material Price Shifts for Citrus aurantium and Market Projections

Recent shifts in Citrus aurantium raw material pricing across domestic harvesting hubs have drawn industry attention. As the new harvest concludes, price stability is key for planning extract supplies.

CPHI China 2025 Invite

Chengdu Chenlv Herb Invites Partners to Explore Plant Extraction at CPHI China 2025

As a leading showcase for China's pharmaceutical ingredients on the global stage, the 23rd China Pharmaceutical Raw Materials Exhibition (CPHI China 2025) will host our team to discuss new extraction technologies.

92nd API Conference Invite

Chengdu Chenlv Herb Invites You to Attend the 92nd API Conference

Join us at the upcoming API conference, where we will highlight our latest research in bioactive carotenoids, botanical APIs, and our verified manufacturing processes.

Frequently Asked Questions

Get answers to technical, regulatory, and logistics questions about our Actase Lutein Za manufacturing.

Q1: What is the exact ratio of carotenoids in your Actase Lutein Za formulation?
Our standard formulation provides the clinically backed 10:10:2 ratio (10mg Lutein, 10mg Meso-Zeaxanthin, and 2mg Zeaxanthin). We can also customize this ratio to meet your specific brand requirements.
Q2: How does CE Certification benefit global buyers of Actase Lutein Za?
CE Certification indicates that the raw material meets EU safety, health, and environmental standards. It simplifies importing into the European Economic Area (EEA) and reassures buyers of product quality.
Q3: How do you verify the presence of Meso-Zeaxanthin compared to other isomers?
We use Chiral High-Performance Liquid Chromatography (Chiral-HPLC). This method separates Lutein, Zeaxanthin, and Meso-Zeaxanthin, allowing us to confirm the exact levels of each isomer.
Q4: What raw materials are used for extraction?
We extract our carotenoids from marigold flowers (Tagetes erecta L.). The flowers are sourced from monitored plantations to ensure low levels of pesticides and heavy metals.
Q5: Which product formats are available for Actase Lutein Za?
We supply oil suspensions (suitable for softgels), beadlet powders (ideal for tablets and hard capsules), and cold-water-dispersible (CWD) powders (well-suited for functional beverages and sachet formulations).
Q6: What is the shelf life and storage conditions for these carotenoid products?
When stored in its original, unopened packaging in a cool (below 15°C), dry place away from direct light, the product has a shelf life of 24 months. We package under nitrogen gas to prevent oxidation.
Q7: Can you customize the formulation with additional active ingredients?
Yes. Through our OEM/ODM customization process, we can combine Actase Lutein Za with zinc, bilberry extract, astaxanthin, or vitamins to create a complete eye health supplement.
Q8: How does your factory handle heavy metal and pesticide testing?
Every production run is tested in-house using ICP-MS for heavy metals. We also screen for pesticide residues, ensuring compliance with both USP and European Pharmacopoeia (EP) regulations.
Q9: What is the minimum order quantity (MOQ) for custom formulations?
Our standard catalog items have an MOQ of 25kg. For custom ratios, beadlet specifications, or special packaging, the MOQ typically ranges between 50kg and 100kg depending on formulation requirements.
Q10: What compliance certificates do you provide with each shipment?
Every shipment includes a Certificate of Analysis (CoA), Safety Data Sheet (SDS), Allergen Statement, Non-GMO Declaration, and BSE/TSE-free certification.