Discover our highly purified, bio-optimized botanical ingredients processed under global compliance protocols.








Actase Lutein Za represents a major leap forward in targeted ophthalmic nutrition. It is designed to mimic the natural composition of the human macular pigment. The macular pigment is situated in the central region of the retina, called the macula lutea. This area is responsible for high-acuity, sharp, and detailed vision. Clinical investigations have confirmed that the macular pigment is composed of three dietary carotenoids: Lutein, Zeaxanthin, and Meso-Zeaxanthin. The synergistic ratio of these three pigments functions as a "natural blue-light filter," absorbing damaging shortwave light radiation and mitigating local oxidative stress.
As a CE certified Actase Lutein Za manufacturer, we focus on delivering raw material configurations that meet strict European Union safety and efficacy standards. CE Certification validates that our ophthalmic-grade raw materials satisfy the essential health, safety, and environmental protection benchmarks. Our advanced production technology isolates, purifies, and stabilizes these macular carotenoids, ensuring optimal bioavailability for downstream formulation.
"Clinical trials such as the Age-Related Eye Disease Study 2 (AREDS2) and the CREST (Central Retinal Enrichment Supplement Trials) have demonstrated that supplementing with the three macular carotenoids (Lutein, Zeaxanthin, and Meso-Zeaxanthin) significantly improves Macular Pigment Optical Density (MPOD) and enhances contrast sensitivity in both healthy individuals and patients suffering from early-stage Age-Related Macular Degeneration (AMD)."
While Lutein and Zeaxanthin are widely found in green leafy vegetables and yellow fruits, Meso-Zeaxanthin is rarely present in the typical human diet. Meso-zeaxanthin is primarily synthesized in the retina from ingested lutein. However, as the human body ages, or due to metabolic imbalances, the enzymatic conversion rate of lutein to meso-zeaxanthin drops significantly. Supplying pre-formed Meso-Zeaxanthin directly through Actase Lutein Za formulations bypasses this metabolic bottleneck.
Our manufacturing facility uses advanced bio-isomerization techniques to convert high-purity lutein extracted from marigold flowers (Tagetes erecta L.) into premium-grade Meso-Zeaxanthin. This allows us to supply the optimal clinical ratio of 10mg Lutein, 10mg Meso-Zeaxanthin, and 2mg Zeaxanthin. This ratio is ideal for maximizing ocular protection and pigment density.
| Carotenoid Spec. | Source Material | Typical Assay Methods | Primary Function in Retina |
|---|---|---|---|
| Lutein (Free/Ester) | Marigold Flowers (Tagetes erecta) | HPLC / UV-Vis | Filters peripheral blue light, scavenger of free radicals. |
| Zeaxanthin | Marigold Flowers / Lycium barbarum | HPLC | Protects mid-peripheral retina, enhances contrast sensitivity. |
| Meso-Zeaxanthin | Synthesized / Bio-isomerized Lutein | Chiral-HPLC | Dominates the fovea centralis, shields high-acuity photodetectors. |
Chengdu ChenLv Herb Co.,Ltd. (referred to as "Chenlv Herb") was established in 2012 as a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts and natural pharmaceutical ingredients. Committed to providing high-purity, highly active, and premium-quality natural raw materials, the company serves diverse industries, including pharmaceuticals, health supplements, food, and cosmetics.
We are situated in the center of botanical innovation in Southwest China. Chenlv Herb utilizes state-of-the-art extraction technology and enforces rigorous testing procedures to make sure our products exceed international health and safety regulations.
Choose Chenlv Herb for products that deliver beyond expectations, built upon a foundation of scientific integrity.
China has become a major global hub for the extraction of carotenoids. This is thanks to natural raw material reserves, integrated industrial supply chains, and advanced engineering technologies. Chengdu Chenlv Herb Co., Ltd. leverages these advantages to offer a stable, high-purity, and cost-effective supply of Actase Lutein Za.
For years, eye health products relied solely on Lutein. However, recent clinical studies have highlighted the importance of Meso-Zeaxanthin. Modern macular health science shows that Meso-Zeaxanthin is concentrated in the foveal region, which handles central, high-resolution vision. Lutein is found in the peripheral area, and Zeaxanthin occupies the mid-peripheral zone.
Because of this, global brands are shifting from simple lutein formulations to triple-carotenoid combinations. The market for products like Actase Lutein Za is growing. Driving factors include an aging population, rising screen time from digital devices, and a growing consumer focus on proactive, preventive health.
Providing versatile and bioavailable active ingredients optimized for diverse global industries.
Chenlv Herb provides one-stop contract manufacturing and optimization services for global brands.
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Communicate with clients to analyze formulation ideas and establish technical product requirements.
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Provide a comprehensive project proposal and commercial quote based on production specifications.
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Finalize contract terms, establish quality agreements, and define delivery milestones.
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Synthesize lab-scale pilot samples and run initial purity and stability tests.
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Upon sample approval, schedule large-scale manufacturing at our certified facility.
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Conduct chemical assays, microbiological screening, and issue the Certificate of Analysis (CoA).
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Coordinate customs clearance, logistics, and ship final goods with comprehensive compliance documentation.
Our manufacturing system is certified by ISO9001, ISO22000, HALAL, KOSHER, FDA, and CE compliant standards.
For brands seeking market differentiation, Actase Lutein Za can be formulated into a variety of delivery formats:
B2B raw material procurement requires strict quality verification. Large international buyers must evaluate several key criteria:
Keep track of our technological innovations, upcoming trade conferences, and raw material market trends.
Recent shifts in Citrus aurantium raw material pricing across domestic harvesting hubs have drawn industry attention. As the new harvest concludes, price stability is key for planning extract supplies.
As a leading showcase for China's pharmaceutical ingredients on the global stage, the 23rd China Pharmaceutical Raw Materials Exhibition (CPHI China 2025) will host our team to discuss new extraction technologies.
Join us at the upcoming API conference, where we will highlight our latest research in bioactive carotenoids, botanical APIs, and our verified manufacturing processes.
Get answers to technical, regulatory, and logistics questions about our Actase Lutein Za manufacturing.
Discover more high-purity, standardized herbal extracts and natural ingredients.