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A technical whitepaper examining the structural profile, modern extraction methodologies, and scientific benchmarks of Rutoside.
Rutin (Quercetin-3-O-rutinoside), scientifically defined as Rutoside, is a low-toxicity flavonol glycoside comprised of quercetin and the disaccharide rutinose. Principally extracted from the dried flower buds of Sophora japonica L., rutoside undergoes strict extraction processes to yield stable structures that bolster cellular protection, enhance vascular microcirculation, and defend against physiological oxidative stress.
The industrial isolation of high-yield Rutoside depends on specific thermo-hydrodynamic crystallization. Utilizing safe food-grade ethanol and purified water, raw plant structures undergo counter-current extraction, followed by membrane filtration, crystallization, and vacuum spray-drying. The resulting fine powder satisfies global pharmacopoeia mesh benchmarks with zero toxic residues.
Standardized Rutin products act as highly effective bioflavonoids. They aid vascular integrity by lowering capillary permeability and fragility, while improving vitamin C absorption. This makes Rutoside a foundational active ingredient in complex therapeutics for venous insufficiency, chronic microangiopathy, and anti-aging cosmetics.
| Parameter | Specification Standard | Testing Methodology | Compliance Reference |
|---|---|---|---|
| Assay (Anhydrous Basis) | 95.0% – 101.5% | HPLC / UV-VIS Spectroscopy | EP / USP / NF11 |
| Identification | Positive Reaction / IR Absorption | Infrared Spectrophotometry | USP Standards |
| Loss on Drying | 5.5% – 9.0% | Thermogravimetric Oven Drying | EP Standard Method |
| Heavy Metals (as Pb) | ≤ 10 ppm | ICP-MS | USP <233> |
| Pesticide Residues | Complies with EC 396/2005 | GC-MS / LC-MS | Ph. Eur. 2.8.13 |
| Microbiological Limits | TAMC ≤ 1000 cfu/g, TYMC ≤ 100 cfu/g | Plate Count Method | USP <61> & <62> |
Chengdu Chenlv Herb Co., Ltd.
Chengdu ChenLv Herb Co.,Ltd. (referred to as "Chenlv Herb") was established in 2012 as a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts and natural pharmaceutical ingredients. Committed to providing high-purity, highly active, and premium-quality natural raw materials, the company serves diverse industries, including pharmaceuticals, health supplements, food, and cosmetics.
Operating out of a highly automated, GMP-certified facility, we utilize modern phyto-extraction processes to isolate vital biological flavonoids, saponins, and organic acids. Our manufacturing systems ensure total molecular stability and structural purity, answering the regulatory requirements of global markets across Europe, North America, and the Asia-Pacific region.
How we address strict quality demands, raw material sustainability, and regional logistics hurdles for large-scale enterprise buyers.
We source raw materials from dedicated agricultural bases, protecting our supply chain from price volatility and agricultural risks. Our factory processes tons of raw *Sophora japonica* daily, guaranteeing a steady supply of premium Rutoside even during seasons of high demand.
Different product lines require distinct physical properties. We offer custom micronization services, creating Rutoside powders with particle sizes down to 200 mesh. This improves solubility in cosmetics and tableting performance in pharmaceutical presses.
We handle international customs compliance, providing full documentation including COAs, MSDS, Phytosanitary Certificates, and export clearances. Our partnerships with top global shippers ensure safe, temperature-controlled delivery to warehouses worldwide.
Choose Chenlv Herb for products that deliver beyond expectations, backed by science and certified processes.
Creative designs and tailored active ingredients that elevate your brand and improve product performance.
Eco-friendly packaging aligned with modern environmental values. Optimized workflow systems guarantee rapid processing.
End-to-end green manufacturing solutions designed to reduce chemical footprints and conserve natural ecosystems.
Accelerated turnaround cycles across all production stages to ensure your supply lines run uninterrupted.
Our dedicated quality control team checks every batch against strict standards, from raw materials to finished products.
With years of bio-extraction expertise, our team ensures precise formulations and outstanding production quality.
Our botanical extracts serve as foundational raw materials across diverse modern industries.
Driven by the concept of "homology of medicine and food" and modern health needs, plant extracts have become core raw materials for health supplements due to their natural, green, and safe characteristics.
From herbal formulas recorded in ancient books to modern innovative drugs, plant extracts hold a prominent position in the pharmaceutical industry due to their active ingredients and unique pharmacological profiles.
With consumers pursuing natural, safe, and sustainable skincare, plant extracts have become favorites in cosmetics, offering mild, versatile, and bio-compatible solutions for modern skincare formulations.
Plant extracts show great potential in supporting animal health, enhancing performance, and optimizing feed systems, making them a growing area of interest in the animal nutrition industry.
Chenlv Herb provides a seamless, one-stop contract manufacturing and optimization service.
Communicate with customers to determine product specifications and design requirements.
Provide a proposal and detailed cost breakdown based on customer specifications.
Sign a contract and finalize terms to begin manufacturing cooperation.
Create pilot-scale samples for the customer's laboratory testing and evaluation.
Following sample approval, our factory schedules and begins full-scale batch production.
We test the finished batch and issue a formal Certificate of Analysis (COA).
Pack and ship the products safely, ensuring prompt delivery to the client's destination.
Our facility operates under rigorous international quality certifications, including ISO9001, ISO22000, HALAL, KOSHER, and FDA registrations.
Crucial technical questions and answers designed for quality control heads and purchasing managers.
Stay informed with updates on phyto-extraction innovations, global pricing trends, and upcoming pharmaceutical trade events.
Recently, the market price of Citrus aurantium raw materials in China has been rising, drawing significant attention from the industry. As the new production season (May-June) comes to an end and new supplies enter the market, price fluctuations have become a focal point due to supply and demand dynamics and production cost considerations.
As a leading platform for China's pharmaceutical industry on the global stage, the 23rd China Pharmaceutical Raw Materials Exhibition (CPHI China 2025) will join hands with the 18th China Pharmaceutical Machinery to present the latest innovations.
We invite you to attend the 92nd API conference to explore new chapters in biotechnology, sustainable raw material sourcing, and pharmaceutical extraction standards alongside our lead research scientists.
For inquiries about our products or custom price list, leave your email below. Our sales and engineering teams will reply within 24 hours.
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